"President Bush's campaign against what he once termed the "axis of evil" has suffered reverses on all three fronts in recent days that underscore the profound challenges confronting him 3 1/2 years after he vowed to take action. First, multilateral talks orchestrated by the United States to pressure North Korea to give up nuclear weapons adjourned last week after 13 days without agreement. Then Iran restarted its program to convert uranium, in defiance of the United States and Europe. Finally, negotiators in Iraq failed to draft a new constitution by Monday's deadline amid an unrelenting guerrilla war against U.S. forces."